Association of Polymorphisms in Vitamin D-Metabolizing Enzymes DHCR7 and CYP2R1 with Cancer Susceptibility: A Systematic Review and Meta-Analysis
Table 5
False-positive report probability values for correlations between genotype frequency of DHCR7 and CYP2R1 and cancer risk.
Genotype
OR (95% CI)
value
Statistical powera
Prior probabilityb
0.25
0.1
0.01
0.001
0.0001
rs12785878 (T/G)
GT vs. TT (overall)
1.168 (1.027-1.328)
0.018
0.312
0.235
0.390
0.853
0.983
0.998
GT vs. TT (Caucasian)
1.178 (1.021-1.358)
0.024
0.271
0.321
0.496
0.899
0.989
0.999
GT vs. TT (PB)
1.193 (1.028-1.385)
0.02
0.264
0.288
0.457
0.885
0.986
0.999
rs1790349 (A/G)
GA vs. AA (Caucasian)
1.201 (1.008-1.431)
0.04
0.290
0.424
0.605
0.933
0.993
0.999
rs12794714 (G/A)
AA vs. GG (CRC)
0.866 (0.753-0.997)
0.046
0.367
0.401
0.582
0.927
0.992
0.999
Note: CI: confidence interval; OR: odds ratio; astatistical power was computed using the sample size of case and control, OR, and values; bthe false-positive report probability is in italics if the .
