Fibrinogen Level Predicts Outcomes in Critically Ill Patients with Acute Exacerbation of Chronic Heart Failure

Table 2

Association between fibrinogen and 90-day mortality.

	Fibrinogen level (mg/dl)	Hazard ratio	95% CI	value
Crude	<284	Ref		<0.0001
	≥284	3.33	2.15-5.15
Model 1	<284	Ref		<0.0001
	≥284	3.35	1.95-5.76
Model 2	<284	Ref		<0.0001
	≥284	3.11	1.81-5.36
Model 3	<284	Ref		<0.0001
	≥284	3.13	1.82-5.40
Model 4	<284	Ref		<0.0001
	≥284	2.83	1.63-4.90
Model 5	<284	Ref		<0.0001
	≥284	2.85	1.65-4.92

Adjusted covariates: model 1 = fibrinogen, PLT, NT-proBNP, vasopressor use, and ventilator use; model 2 = model 1+HBP, Af, respiratory failure, CKD, and STEMI; model 3 = model 2+SIRS scores (VIF 4.24); model 4 = model 2+APS III scores (VIF 3.94); model 5 = model 2+SAPS II scores (VIF 4.22).