Handgrip Strength and Vitamin D as Predictors of Liver Fibrosis and Malnutrition in Chronic Hepatitis C Patients
Table 5
Stepwise multiple regression analysis for malnutrition predicted by adiposity, liver fibrosis, muscle mass scores (MAC, MAMC, and TSF), HGS, SGA malnutrition scores, and vitamin D deficiency in CHC patients with significant fibrosis and cirrhosis.
Variables
Significant fibrosis (F2-F3)
Significant cirrhosis (F4)
95% CI
95% CI
Adiposity (BMI)
4.6 (0.35)
89 (75–100)
5.9 (0.38)
86 (75–98)
Vitamin D deficiency
23.8 (0.42)
92 (82–98)
16.9 (0.62)
81 (68–96)
Ca and vitamin D intake
5.6 (0.53)
75 (65–89)
6.3 (0.47)
90 (88–100)
MAC
2.8 (0.28)
84 (72–92)
4.3 (0.32)
94 (88–100)
MAMC
3.6 (0.22)
65 (55–90)
5.3 (0.32)
78 (88–100)
TSF
1.6 (0.29)
76 (65–89)
4.6 (0.37)
84 (88–100)
SGA
3.7 (0.33)
79 (68–92)
5.8 (0.48)
91 (82–100)
HGS
4.1 (0.53)
89 (65–89)
6.8 (0.51)
96 (88–100)
HYP (lg/mL)
2.6 (0.33)
91 (80–100)
3.9 (0.25)
97 (88–100)
HA (ng/mL)
3.6 (0.31)
95 (80–100)
4.9 (0.31)
89 (88–100)
FN (ng/mL)
1.6 (0.21)
91 (86–100)
3.9 (0.38)
95 (88–100)
APRI
2.6 (0.35)
98 (86–100)
4.5 (0.41)
98 (85–100)
Hyp index
4.2 (0.41)
87 (76–98)
5.9 (0.46)
90 (85–100)
FNPRI index
3.2 (0.52)
89 (72–96)
4.9 (0.39)
89 (82–100)
HAPRI
2.9 (0.61)
93 (76–96)
5.6 (0.68)
96 (82–100)
(%)
70.5 (0.38)
96 (76–96)
89.6 (0.39)
98 (88–100)
and . of cumulative values of relating to studied variables. CI: confidence interval; BMI: body mass index; MAC: midarm circumference in cm; TSF: triceps skin fold thickness in mm; MAMC: midarm muscle circumference in mm; CHC patients: chronic hepatitis C patients; SGA: subjective global assessment; HYP: hydroxyproline; HA: hyaluronic acid; FN: fibronectin; APRI: AST to platelet ratio index; Hyp index: hydroxyproline to platelet ratio index; HAPRI: HA to platelet ratio index; FNPRI: FN to platelet ratio index.
