Research Article
The Value of a Seven-Autoantibody Panel Combined with the Mayo Model in the Differential Diagnosis of Pulmonary Nodules
Table 2
Baseline characteristics and performances of the patients with PN.
| | Parameters | Advanced stage MPN () | Early-stage MPN () | BPN () | value |
| | Age, median (range) | 61.4 (40.0-82.0) | 54.2♀ (28.0-77.0) | 51.1 (29.0-75.0) | <0.01 | | Sex, (%) | | | | | | Male | 94 (81.0) | 47 (61.0)♀ | 86 (53.1) | <0.0001 | | Female | 22 (19.0) | 30 (39.0) | 76 (46.9) | | | Smoking, (%) | | | | | | Ever/current | 86 (74.1) | 42 (54.5) | 49 (30.2) | <0.0001 | | Never | 30 (25.9) | 35 (45.5) | 113 (69.8) | | | Nodule size, (%) | | | | | | ≤8 mm | 10 (8.6) | 31(40.3) | 134 (83.8) | <0.0001 | | 9 mm-30 mm | 28 (24.2) | 45 (58.4) | 20 (12.3) | <0.0001 | | >30 mm | 78 (67.2) | 1 (1.3)♀ | 8 (4.9) | <0.0001 | | 7-AABs, (%) | | | | | | Positive | 70 (60.3) | 52 (67.5) | 42 (25.9) | <0.0001 | | Negative | 46 (39.7) | 25 (32.5) | 120 (74.1) | | | Mayo model, (%) | | | | | | <5% | 4 (3.4) | 28 (36.4) | 100 (61.7) | <0.0001 | | 5–65% | 32 (27.6)♀ | 42 (54.5) | 56 (34.6) | 0.001 | | >65% | 80 (69.0) | 7 (9.1)♀ | 6 (3.7) | <0.0001 |
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PN = pulmonary nodule; MPN = malignant pulmonary nodule; BPN = benign pulmonary nodule. Compared to BPN, <0.05, <0.001, <0.0001, and ♀>0.05. |
