Prognostic Significance of the Combined Score of Plasma Fibrinogen and Neutrophil-Lymphocyte Ratio in Patients with Spontaneous Intracerebral Hemorrhage

Table 4

Predictive models for predicting primary outcomes of ICH patients.

(a)

Original cohort	3-month functional outcome		Original cohort	1-month mortality
Predictive models	C-index	AIC	Predictive models	C-index	AIC
Basic model^§	0.8616	339.4594	Basic model^†	0.8203	330.1387
Basic model+fibrinogen	0.8729	331.9510	Basic model+fibrinogen	0.8518	306.0032
Basic model+NLR	0.8634	338.3470	Basic model+NLR	0.8460	318.2431
Basic model+F-NLR score	0.8731	329.4173	Basic model+F-NLR score	0.8589	306.0029

(b)

Validation cohort	3-month functional outcome		Validation cohort	1-month mortality
Predictive models	C-index	AIC	Predictive models	C-index	AIC
Basic model^‡	0.8108	240.9239	Basic model	0.7834	179.8238
Basic model+fibrinogen	0.8319	232.0876	Basic model+fibrinogen	0.8362	162.7893
Basic model+NLR	0.8300	232.9518	Basic model+NLR	0.8591	149.2128
Basic model+F-NLR score	0.8694	209.8464	Basic model+F-NLR score	0.8876	147.3019

^§Basic model: GCS, hematoma volume, hematoma location, treatment;^†basic model: GCS, hematoma volume, presence of IVH, PT;^‡Basic model: GCS, hematoma location, treatment;basic model: GCS, hematoma volume, presence of HE, PLT, PT. Abbreviation: GCS, Glasgow Coma Scale; IVH, intraventricular hemorrhage; HE, hematoma expansion; PLT, platelet; PT, prothrombin time; C-index, Harrell’s concordance index; AIC, Akaike information criterion; F, fibrinogen; NLR, neutrophil to lymphocyte ratio; OR, odds ratio; CI, confidence interval.