Research Article
Protective Effect of Fasudil on Hydrogen Peroxide-Induced Oxidative Stress Injury of H9C2 Cardiomyocytes
Figure 6
Fasudil inhibits Rho/ROCK pathway activation. (a) Western blot analysis of ROCK1, ROCK2, p-MYPT-1, and MYPT-1 expression in three groups. GAPDH was used as an internal control. (b) Protein gray value ratio of p-MYPT-1/MYPT-1. (c, d) ROCK1 and ROCK2 mRNA expression was determined by real-time PCR (“” indicates statistical difference from the control group , and “#” indicates statistical difference from the ischemic hypoxia group ).
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