Research Article
VDR Gene Polymorphisms in Healthy Individuals with Family History of Premature Coronary Artery Disease
Table 3
FokI polymorphism of the VDR gene and FH of P-CAD.
| | FokI (rs2228570) | All
n (%)
845 (100) | Study population with FH of P-CAD
(%)
386 (45.68) | Control group
(%)
459 (54.32) | OR (95% CI) | value |
| | Codominant | | | | | | | AA | 173 (20.47) | 95 (24.61) | 78 (16.99) | 1.27 (1.04-1.55) | 0.017 | | AG | 428 (50.65) | 186 (48.19) | 242 (52.72) | 1.01 (0.86-1.18) | 0.915 | | GG | 244 (28.88) | 105 (27.20) | 139 (30.28) | 1.00 (ref.) | |
| | Dominant | | | | | | | AG + AA | 601 (71.12) | 281 (72.80) | 320 (69.72) | 1.08 (0.93-1.25) | 0.325 | | GG | 244 (28.88) | 105 (27.20) | 139 (30.28) | 1.00 (ref.) | |
| | Recessive | | | | | | | AA | 173 (20.47) | 95 (24.61) | 78 (16.99) | 1.26 (1.07-1.49) | 0.007 | | AG + GG | 672 (79.53) | 291 (75.39) | 381 (83.01) | 1.00 (ref.) | |
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