A Risk Signature with Autophagy-Related Long Noncoding RNAs for Predicting the Prognosis of Clear Cell Renal Cell Carcinoma: Based on the TCGA Database and Bioinformatics

Table 2

Functional enrichment analyses of the prognostic autophagy-related lncRNAs.

Category	ID	Description	value	FDR	Genes
Biological process	GO:0000422	Mitophagy	4.97-04	0.038125	PINK1, CDKN2A, ATG4B
Biological process	GO:0018017	Peptidyl-threonine phosphorylation	5.87-04	0.038125	MAPK8, BCL2, MAPK1
Biological process	GO:0045727	Positive regulation of translation	1.14-03	0.063524	PINK1, ERBB2, MAPK1
Biological process	GO:0016236	Macroautophagy	4.78-05	0.006217	PINK1, NBR1, ATG4B, PIK3C3
Biological process	GO:0006950	Response to stress	1.50-03	0.073488	PINK1, MAPK8, MAPK1
Biological process	GO:0031647	Regulation of protein stability	1.98-03	0.002612	CDKN2A, BCL2, MAPK1
Biological process	GO:0006914	Autophagy	6.36-06	0.001240	PINK1, NBR1, ATG4B, PIK3C3
Biological process	GO:0018105	Peptidyl-serine phosphorylation	2.10-04	0.020483	PINK1, MAPK8, BCL2, MAPK1
Biological process	GO:0006468	Protein phosphorylation	2.47-06	9.62E-04	IKBKB, PINK1, MAPK8, ERBB2, MAPK1, BICR5, PIK3C3
Cellular component	GO:0005776	Autophagosome	1.4-03	0.029687	NBR1, RAB24, WDFY3
Cellular component	GO:0005770	Late endosome	5.0-03	0.069394	NBR1, MAPK1, PIK3C3
Cellular component	GO:0005739	Mitochondrion	6.94-05	0.002878	PINK1, MAPK8, CDKN2A, CAPN10, RAB24, BCL2, MAPK1
Cellular component	GO:0005622	Intracellular	6.37-04	0.017625	IKBKB, MAPK8, HGS, CAPN10, RAB24, MAPK1, PIK3C3
Cellular component	GO:0005737	Cytoplasm	5.0-03	0.069395	IKBKB, PINK1, CDKN2A, HGS, ERBB2, BCL2, ULK3, ATG4B, MAPK1, BIRC5, WDFY3
Molecular function	GO:0016301	Kinase activity	3.58-08	2.68E-06	PINK1, MAPK8, CDKN2A, HGS, ERBB2, MAPK1, PIK3C3,
Molecular function	GO:0004672	Protein kinase activity	2.28-04	0.006804	IKBKB, PINK1, ERBB2, ULK3, PIK3C3
Molecular function	GO:0004674	Protein serine/threonine kinase activity	0.00406432.72-04	0.020892; 0.006803	BIRC5, PINK1; IKBKB, PINK1, MAPK8, ULK3, MAPK1
Molecular function	GO:0046982	Protein heterodimerization activity	0.007382	0.092273	IKBKB, ERBB2, BCL2, BIRC5
Molecular function	GO:0005524	ATP binding	1.2-03	0.017773	IKBKB, PINK1, MAPK8, ERBB2, ULK3, MAPK1, PIK3C3
Molecular function	GO:0004861	Protein binding	8.21-04	0.015391	CDKN2A, IKBKB, PINK1, MAPK8, HGS, NBR1, ERBB2, RAB24, ULK3, BCL2, BIRC5, ATG4B, MAPK1, PIK3C3, WDFY3