Research Article
Expression of Glutamine Metabolism-Related and Amino Acid Transporter Proteins in Adrenal Cortical Neoplasms and Pheochromocytomas
Table 1
Expression of glutamine metabolism-related proteins and amino acid transporter proteins in adrenal gland neoplasm.
| | Parameters | Total
(%) | Adrenal cortical neoplasm
(%) | Pheochromocytoma
(%) | value |
| | GLS | | | | <0.001 | | Negative | 248 (77.3) | 85 (64.4) | 163 (86.2) | | | Positive | 73 (22.7) | 47 (35.6) | 26 (13.8) | | | GDH | | | | 0.956 | | Negative | 316 (98.4) | 130 (98.5) | 186 (98.4) | | | Positive | 5 (1.6) | 2 (1.5) | 3 (1.6) | | | SLC1A5 | | | | 0.049 | | Negative | 242 (75.4) | 107 (81.1) | 135 (71.4) | | | Positive | 79 (24.6) | 25 (18.9) | 54 (28.6) | | | SLC7A5 | | | | 0.007 | | Negative | 316 (98.4) | 127 (96.2) | 189 (100.0) | | | Positive | 5 (1.6) | 5 (3.8) | 0 (0.0) | | | SLC7A11 | | | | <0.001 | | Negative | 259 (80.7) | 126 (95.5) | 133 (70.4) | | | Positive | 62 (19.3) | 6 (4.5) | 56 (29.6) | | | SDHB | | | | <0.001 | | Negative | 189 (58.9) | 47 (35.6) | 142 (75.1) | | | Positive | 132 (41.1) | 85 (64.4) | 47 (24.9) | | | BNIP3 | | | | <0.001 | | Negative | 293 (91.3) | 111 (84.1) | 182 (96.3) | | | Positive | 28 (8.7) | 21 (15.9) | 7 (3.7) | |
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