Research Article
Expression of Glutamine Metabolism-Related and Amino Acid Transporter Proteins in Adrenal Cortical Neoplasms and Pheochromocytomas
Table 2
Expression of glutamine metabolism-related proteins and amino acid transporter proteins in adrenal cortical neoplasm.
| | Parameters | Total
(%) | Adrenal cortical adenoma
(%) | Adrenal cortical carcinoma
(%) | value |
| | GLS | | | | 0.110 | | Negative | 85 (64.4) | 77 (67.0) | 8 (47.1) | | | Positive | 47 (35.6) | 38 (33.0) | 9 (52.9) | | | GDH | | | | 0.114 | | Negative | 130 (98.5) | 114 (99.1) | 16 (94.1) | | | Positive | 2 (1.5) | 1 (0.9) | 1 (5.9) | | | SLC1A5 | | | | 0.141 | | Negative | 107 (81.1) | 91 (79.1) | 16 (94.1) | | | Positive | 25 (5.9) | 24 (20.9) | 1 (5.9) | | | SLC7A5 | | | | 0.124 | | Negative | 127 (96.2) | 112 (97.4) | 15 (88.2) | | | Positive | 5 (3.8) | 3 (2.6) | 2 (11.8) | | | SLC7A11 | | | | 0.335 | | Negative | 126 (95.5) | 109 (94.8) | 17 (100.0) | | | Positive | 6 (4.5) | 6 (5.2) | 0 (0.0) | | | SDHB | | | | 0.007 | | Negative | 47 (35.6) | 36 (31.3) | 11 (64.7) | | | Positive | 85 (64.4) | 79 (68.7) | 6 (35.3) | | | BNIP3 | | | | <0.001 | | Negative | 111 (84.1) | 106 (92.2) | 5 (29.4) | | | Positive | 21 (15.9) | 9 (7.8) | 12 (70.6) | |
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