Expression of Glutamine Metabolism-Related and Amino Acid Transporter Proteins in Adrenal Cortical Neoplasms and Pheochromocytomas

Table 3

Expression of glutamine metabolism-related proteins and amino acid transporter proteins according to SDHB status in pheochromocytoma.

Parameters	SDHB negative; (%)	SDHB positive; (%)	value
GLS			<0.001
Negative	130 (91.5)	33 (70.2)
Positive	12 (8.5)	14 (29.8)
GDH			0.153
Negative	141 (99.3)	45 (95.7)
Positive	1 (0.7)	2 (4.3)
SLC1A5			0.014
Negative	108 (76.1)	27 (57.4)
Positive	34 (23.9)	20 (42.6)
SLC7A5			n/a
Negative	142 (100.0)	47 (100.0)
Positive	0 (0.0)	0 (0.0)
SLC7A11			0.001
Negative	109 (76.8)	24 (51.1)
Positive	33 (23.2)	23 (48.9)
BNIP3			0.066
Negative	139 (97.9)	43 (91.5)
Positive	3 (2.1)	4 (8.5)