Expression of Glutamine Metabolism-Related and Amino Acid Transporter Proteins in Adrenal Cortical Neoplasms and Pheochromocytomas

Table 4

Expression of glutamine metabolism-related proteins and amino acid transporter proteins according to BNIP3 status in adrenal gland neoplasm.

Parameters	Adrenal cortical neoplasm			Pheochromocytoma
	BNIP3 negative; (%)	BNIP3 positive; (%)	value	BNIP3 negative; (%)	BNIP3 positive; (%)	value
GLS			0.080			0.008
Negative	75 (67.6)	10 (47.6)		160 (87.9)	3 (42.9)
Positive	36 (32.4)	11 (52.4)		22 (12.1)	4 (57.1)
GDH			0.024			0.003
Negative	111 (100.0)	19 (90.5)		181 (99.5)	5 (71.4)
Positive	0 (0.0)	2 (9.5)		1 (0.5)	2 (28.6)
SLC1A5			0.002			0.410
Negative	95 (85.6)	12 (57.1)		131 (72.0)	4 (57.1)
Positive	16 (14.4)	9 (42.9)		51 (28.0)	3 (42.9)
SLC7A5			<0.001			n/a
Negative	111 (100.0)	16 (76.2)		182 (100.0)	7 (100.0)
Positive	0 (0.0)	5 (23.8)		0 (0.0)	0 (0.0)
SLC7A11			<0.001			0.425
Negative	111 (100.0)	15 (71.4)		129 (70.9)	4 (57.1)
Positive	0 (0.0)	6 (28.6)		53 (29.1)	3 (42.9)