Research Article

m6A RNA Methylation Regulators Elicit Malignant Progression and Predict Clinical Outcome in Hepatocellular Carcinoma

Table 1

Characteristics of patients with HCC in TCGA and ICGC cohorts.

Clinical characteristicsTotal%

TCGA370
 Survival statusSurvival24465.95
Death12634.05
 Age≤65 years23262.70
>65 years13837.30
 GenderMale24967.30
Female12132.70
 Histological gradeG15514.86
G217747.84
G312132.70
G4123.24
 StageI17146.22
II8522.97
III8522.97
IV51.35
 T classificationT118148.92
T29325.14
T38021.62
T4133.51
TX10.27
 M classificationM026671.89
M141.08
MX10027.03
 N classificationN025268.11
N141.08
NX11330.54

ICGC232

 Survival statusSurvival18981.47
Death4318.53
 Age≤65 years9038.79
>65 years14261.21
 GenderMale17173.71
Female6126.29
 StageI3615.52
II10645.69
III7130.60
IV198.19
 Prior malignancyNo20287.07
Yes3012.93

GSE14520209

 Survival statusSurvival13062.20
Death7937.80

Abbreviations: TCGA: The Cancer Genome Atlas; ICGC: International Cancer Genome Consortium.