Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer
Table 1
Gene sets enriched in the high DNA2 expression phenotype.
Gene set name
NES
NOM -val
FDR -val
KEGG_CELL_CYCLE
2.5039673
0
0
KEGG_OOCYTE_MEIOSIS
2.5004425
0
0
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION
2.2601042
0
7.58E-04
KEGG_BASAL_TRANSCRIPTION_FACTORS
2.2252226
0
9.09E-04
KEGG_RNA_DEGRADATION
2.1981418
0
9.48E-04
KEGG_SPLICEOSOME
2.1785731
0
9.70E-04
KEGG_DNA_REPLICATION
2.1734233
0
8.31E-04
KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS
2.0631318
0.001960784
0.00491828
KEGG_HOMOLOGOUS_RECOMBINATION
2.061698
0
0.004467648
KEGG_MISMATCH_REPAIR
2.0155804
0
0.0078261
KEGG_PYRIMIDINE_METABOLISM
1.9722291
0
0.01263749
KEGG_NUCLEOTIDE_EXCISION_REPAIR
1.9698429
0.006237006
0.011753452
KEGG_BASE_EXCISION_REPAIR
1.9483268
0
0.013909859
KEGG_P53_SIGNALING_PATHWAY
1.9202973
0.002020202
0.017711155
KEGG_AMINOACYL_TRNA_BIOSYNTHESIS
1.91081
0.004264392
0.018946456
KEGG_PURINE_METABOLISM
1.9019014
0
0.019136654
KEGG_CYSTEINE_AND_METHIONINE_METABOLISM
1.8780447
0.004
0.022393785
KEGG_LYSINE_DEGRADATION
1.8466676
0.003944773
0.029533371
KEGG_ONE_CARBON_POOL_BY_FOLATE
1.8179266
0.008
0.035526518
NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate. Gene sets with NOM value <0.05 and FDR value <0.05 were regarded as significantly enriched.
