| | Variables | Total () | Unruptured () | Ruptured () | value |
| | Age, y, mean (SD) | 29.6 (14.0) | 31.0 (13.1) | 28.2 (14.6) | 0.221 | | Sex, male (%) | 79 (55.2) | 37 (53.6) | 42 (56.8) | 0.706 | | Medical history (%) | | | | | | Hypertension | 9 (6.3) | 2 (2.9) | 7 (9.5) | 0.204 | | Diabetes mellitus | 3 (2.1) | 1 (1.4) | 2 (2.7) | 1.000 | | Hyperlipidemia | 1 (0.7) | 0 (0) | 1 (1.4) | 1.000 | | Cigarette smoking | 26 (18.2) | 12 (17.4) | 14 (18.9) | 0.813 | | Alcohol drinking | 16 (11.2) | 7 (10.1) | 9 (12.2) | 0.702 | | Prior treatments (%) | | | | | | Embolization | 21 (14.7) | 7 (10.1) | 14 (18.9) | 0.139 | | Radiosurgery | 6 (4.2) | 1 (1.4) | 5 (6.8) | 0.244 | | Microsurgery | 5 (3.5) | 2 (2.9) | 3 (4.1) | 1.000 | | Primary symptom (%) | | | | | | Hemorrhage | 74 (51.7) | 0 (0) | 74 (100.0) | <0.001 | | Seizure | 30 (21.0) | 25 (36.2) | 5 (6.8) | <0.001 | | Neurological dysfunction | 29 (20.3) | 15 (21.7) | 14 (18.9) | 0.675 | | Admission (%) | 15 (10.5) | 1 (1.4) | 14 (18.9) | <0.001 | | AVM characteristics | | | | | | Spetzler-Martin grade (%) | | | | 0.149 | | I-II | 81 (56.6) | 34 (49.3) | 47 (63.5) | | | III | 42 (29.4) | 22 (31.9) | 20 (27.0) | | | IV-V | 20 (14.0) | 13 (18.8) | 7 (9.5) | | | Maximum diameter, cm, median (IQR) | 3.4 (2.5-4.6) | 3.9 (3.0-5.1) | 2.9 (2.3-4.1) | <0.001 | | Volume, cm3, median (IQR) | 8.6 (4.4-25.0) | 15.8 (6.2-33.7) | 6.0 (3.5-15.3) | <0.001 | | Deep location (%) | 33 (23.1) | 16 (23.2) | 17 (23.0) | 0.976 | | Eloquent location (%) | 72 (50.3) | 34 (49.3) | 38 (51.4) | 0.804 | | Deep venous drainage (%) | 43 (30.1) | 21 (30.4) | 22 (29.7) | 0.927 | | Associated aneurysms (%) | 21 (14.7) | 10 (14.5) | 11 (14.9) | 0.950 | | Clinical features, mean (SD) | | | | | | Heart rate, bpm | 80 (10) | 80 (9) | 81 (11) | 0.405 | | SBP, mm Hg | 120 (15) | 120 (13) | 120 (17) | 1.000 | | DBP, mm Hg | 77 (10) | 76 (10) | 78 (11) | 0.434 | | BMI, kg/m2 | 22.6 (4.4) | 23.2 (4.4) | 22.0 (4.4) | 0.099 | | Laboratory results, median (IQR) | | | | | | Glucose, mmol/L | 4.6 (4.3-5.0) | 4.6 (4.3-4.8) | 4.6 (4.4-5.1) | 0.141 | | Albumin, g/L | 43.9 (41.3-46.0) | 44.4 (41.6-46.1) | 43.5 (41.0-45.9) | 0.511 | | Creatinine, μmol/L | 58.6 (46.6-68.5) | 59.5 (49.7-70.9) | 56.2 (45.2-67.8) | 0.109 | | UA, μmol/L | 314.0 (257.7-366.5) | 324.5 (280.8-374.8) | 294.0 (241.8-357.1) | 0.032 | | TC, mmol/L | 4.3 (3.6-4.8) | 4.3 (3.8-4.9) | 4.2 (3.5-4.8) | 0.468 | | TG, mmol/L | 1.0 (0.7-1.5) | 1.1 (0.8-1.6) | 0.9 (0.7-1.5) | 0.130 | | HDL-C, mmol/L | 1.2 (1.0-1.5) | 1.2 (1.0-1.4) | 1.2 (1.1-1.5) | 0.701 | | LDL-C, mmol/L | 2.6 (2.0-3.2) | 2.8 (2.1-3.5) | 2.5 (1.9-3.1) | 0.080 | | ApoA, g/L | 1.3 (1.1-1.4) | 1.3 (1.1-1.4) | 1.3 (1.1-1.4) | 0.588 | | ApoB, g/L | 0.8 (0.7-1.0) | 0.9 (0.7-1.1) | 0.8 (0.7-0.9) | 0.211 | | Hcy, μmol/L | 12.4 (9.9-16.2) | 13.3 (10.4-18.9) | 11.7 (9.7-14.6) | 0.057 | | HHcy (%) | 45 (31.5) | 28 (40.6) | 17 (23.0) | 0.023 |
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