Research Article
Homocysteine Level and Risk of Hemorrhage in Brain Arteriovenous Malformations
Table 3
Logistic regression analysis on the risk of hemorrhage.
| Variables | Univariate analysis | Multivariate analysis | OR | 95% CI | value | OR | 95% CI | value |
| Age | 0.985 | 0.962-1.009 | 0.220 | 0.980 | 0.954-1.007 | 0.154 | Male sex | 1.135 | 0.587-2.196 | 0.707 | 1.565 | 0.686-3.568 | 0.287 | Medical history | | | | | | | Hypertension | 3.500 | 0.701-17.467 | 0.127 | | | | Diabetes mellitus | 1.889 | 0.167-21.311 | 0.607 | | | | Cigarette smoking | 1.108 | 0.473-2.598 | 0.813 | 0.974 | 0.325-2.914 | 0.962 | Alcohol drinking | 1.226 | 0.430-3.495 | 0.703 | | | | Prior treatments | | | | | | | Embolization | 2.067 | 0.780-5.475 | 0.144 | 2.848 | 0.868-9.347 | 0.084 | Radiosurgery | 4.928 | 0.561-43.286 | 0.150 | | | | Microsurgery | 1.415 | 0.229-8.737 | 0.708 | | | | AVM characteristics | | | | | | | Maximum diameter | 0.668 | 0.519-0.859 | 0.002 | 0.634 | 0.479-0.839 | 0.001 | Deep location | 1.012 | 0.465-2.205 | 0.976 | 1.271 | 0.507-3.187 | 0.609 | Eloquent location | 1.087 | 0.564-2.094 | 0.804 | 1.230 | 0.561-2.698 | 0.605 | Deep venous drainage | 0.967 | 0.473-1.977 | 0.927 | 0.914 | 0.391-2.135 | 0.836 | Associated aneurysms | 1.030 | 0.408-2.603 | 0.950 | 1.184 | 0.415-3.380 | 0.753 | Clinical features | | | | | | | Heart rate | 1.014 | 0.981-1.049 | 0.402 | | | | SBP | 1.000 | 0.978-1.022 | >0.999 | | | | DBP | 1.013 | 0.981-1.046 | 0.432 | | | | BMI | 0.937 | 0.867-1.013 | 0.102 | | | | Laboratory results | | | | | | | Glucose | 1.510 | 0.965-2.362 | 0.071 | | | | Albumin | 0.976 | 0.886-1.074 | 0.614 | | | | Creatinine | 0.978 | 0.957-1.000 | 0.051 | | | | UA | 1.000 | 0.999-1.001 | 0.964 | | | | TC | 0.912 | 0.638-1.305 | 0.616 | | | | TG | 1.052 | 0.764-1.449 | 0.756 | | | | HDL-C | 1.819 | 0.851-3.886 | 0.123 | | | | LDL-C | 0.724 | 0.493-1.064 | 0.100 | | | | ApoA | 0.916 | 0.272-3.089 | 0.888 | | | | ApoB | 0.404 | 0.081-2.012 | 0.269 | | | | Hcy | 0.965 | 0.934-0.998 | 0.038 | 0.956 | 0.920-0.993 | 0.021 |
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OR: odds ratio; CI: confidence intervals; AVM: arteriovenous malformation; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; UA: uric acid; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA: apolipoprotein A; ApoB: apolipoprotein B; Hcy: homocysteine. , significant difference. |