Disease Markers

Research Article

The Diagnostic Value of Serum PIVKA-II Alone or in Combination with AFP in Chinese Hepatocellular Carcinoma Patients

Table 1

Baseline characteristics of all the studied groups.


	HCC ()	LC ()	BLD ()	value

Age (years)
Gender (male/female)	271/37	48/12	46/14
Total bilirubin (mg/dl)
AFP (ng/ml)	235.30 (0.70-121000.00)	13.16 (1.46-56.50)	4.99 (0.60-45.78)
PIVKA-II (mAU/ml)	1805.50 (9.00-75000.00)	24.00 (11.00-45.00)	25.00 (12.00-46.00)
AST (U/L)	49.70 (11.80-938.90)	55.60 (11.00-298.00)	18.80 (12.50-39.6)
ALT (U/L)	40.40 (8.6-1265.7)	38.10 (4.00-158.50)	15.85 (3.20-45.30)
ALB (g/L)	39.20 (27.70-52.50)	40.55 (23.90-50.20)	51.20 (33.40-69.20)
PT-INR	1.47 (0.75-1.62)	1.55 (0.75-1.94)	1.89 (0.95-2.44)

Data are the or median (minimum-maximum) values. HCC: hepatocellular carcinoma; LC: liver cirrhosis; BLD: benign liver disease; AFP: alpha-fetoprotein; PIVKA-II: prothrombin induced by vitamin K absence II; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALB: albumin; PT-INR: prothrombin time-international normalized ratio.