Programmed Cell Death Protein Ligand 2 Is a Potential Biomarker That Predicts the Efficacy of Immunotherapy

Figure 2

Survival analysis between the PDL2-high group and the PDL2-low group in the ICI cohorts. (a) Histogram describing proportions of responders in different groups of ICI cohorts; except the Miao cohort and Van Allen cohort, the PDL2-high group has more responders than the PDL2-low group. (b) Univariate Cox analysis according to PDL2 expression median in the ICI cohorts; high PDL2 expression is protective in ICI-treated patients. (c) The percentage decrease of HR caused by high PDL2 expression in the ICI cohort. (d–i) KM plot of OS in ICI cohorts comparing patients with high and low PDL2 expressions and longer OS were observed in the PDL2-high group.

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