Altered Small-World Functional Network Topology in Patients with Optic Neuritis: A Resting-State fMRI Study

Figure 2

Comparison of analysis of small-world attribute of functional brain network between ON patients and HCs. Notes: resting-state small-world parameter analyses showing that both ONs and HCs were consistent with small-world characteristics (, , ). However, compared with the control group, the values of (b) and (c) in ON group increased significantly, and the difference was statistically significant (). There was no significant difference in value (a) between the two groups (). Abbreviation: ON: optic neuritis; HCs: healthy controls; AUC: area under curve; aγ: the AUC of normalized characteristic path length; aλ: the AUC of normalized characteristic path length; aσ: the AUC of small-worldness.

(a)

(b)

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