Disease Markers

Research Article

Altered Small-World Functional Network Topology in Patients with Optic Neuritis: A Resting-State fMRI Study

Table 2

Brain functional connectivity between ON patients and HCs identified by NBS analysis.


Connectivity	value

ROL.L to DCG.L	6.026	<0.05
ROL.L to DCG.R	5.747	<0.05
ROL.R to DCG.L	5.239	<0.05
ROL.R to AMYG.R	5.212	<0.05
SFG med.R to CRBL_Crus6_L	5.205	<0.05
INS.L to DCG.L	6.066	<0.05
INS.L to DCG.R	5.169	<0.05
INS.L to AMYG.L	5.284	<0.05
INS.L to SPG.L	5.129	<0.05
INS.R to DCG.L	5.454	<0.05
INS.R to IPL.R	5.365	<0.05
INS.R to ANG.L	5.071	<0.05
INS.R to ANG.R	5.220	<0.05
INS.R to STG.L	5.085	<0.05
SMG.L to PAL.R	5.444	<0.05
SMG.R to CRBL_6_L	5.257	<0.05

Notes: NBS: , and 5,000 permutations, indicates a significant difference between the groups. Abbreviation: ON: optic neuritis; HCs: healthy controls; ROL: rolandic operculum; SFGmed: superior frontal gyrus, medial; INS: insula; DCG: median cingulate and paracingulate gyri; AMYG: amygdala; SPG: superior parietal gyrus; IPL: inferior parietal gyrus, but supramarginal and angular gyri; SMG: supramarginal gyrus; ANG: angular gyrus; PAL: lenticular nucleus, pallidum; STG: superior temporal gyrus; CRBLCrus1: cerebellum_Crus1; CRBL 6: cerebellum_Crus6; L: left hemisphere; R: right hemisphere.