Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease

<div>JZLGD reduced the expression levels of inflammasome-related proteins and proinflammatory factors involved in canonical pyroptosis signaling in HFD rats. (a) Representative blot and (b–f) quantitative analyses of (b) NLRP3, (c) ASC, (d) caspase-1, (e) IL-1<i>β</i>, and (f) IL-18 protein levels. 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27V0H384Z"></path></g></svg> vs. HFD group.</div>

Disease Markers

fig4

Figure 4

Figure 4: Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease 

Figure 4 | Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease 