Research Article

Machine Learning of Schizophrenia Detection with Structural and Functional Neuroimaging

Table 3

Top 15 most discriminative features for classification.

RegionsALFFDCReHoVMHCGMDWeight

SPL_L_5_2 () ()NS ()NS1.3275
IPL_L_6_2NS () ()NSNS1.2037
MVOcC_L_5_1 () () () ()NS1.1467
ITG_L_7_3 () () ()NSNS1.0778
MFG_L_7_5 () () () () ()0.9969
MVOcC _R_5_1NS () () ()NS0.9484
PhG_L_6_5NS ()NS () ()0.9476
LOcC_L_2_2 () () () ()NS0.9099
FuG_L_3_2 () () () ()NS0.8904
BG_R_6_5NS () () () ()0.8877
MVOcC_R_5_3 () () () ()NS0.8413
CG_R_7_7NSNS () ()NS0.7860
SFG_R_7_2 () () () ()NS0.7672
PhG_R_6_5NS ()NS ()NS0.7664
pSTS_R_2_2NS () () () ()0.7283

NS: not significant, (optimal threshold); positive value means increased values in the SZ group. ALFF: amplitude of low-frequency fluctuations (ALFF); ReHo: regional homogeneity; DC: degree centrality; VMHC: voxel-mirrored homotopic connectivity; SPL: superior parietal lobule; IPL: inferior parietal lobule; MVOcC: medioventral occipital cortex; ITG: inferior temporal gyrus; MFG: middle frontal gyrus; PhG: parahippocampal gyrus; LOcC: lateral occipital cortex; FuG: fusiform gyrus; BG: basal ganglia; CG: cingulate gyrus; SFG: superior frontal gyrus; pSTS: posterior superior temporal sulcus; L: left; R: right.