Serine Protease 3 Promotes Progression of Diffuse Large B-Cell Lymphoma and Serves as a Novel Prognostic Predictor

Figure 4

Silencing PRSS3 impaired DLBCL proliferation. (a) Protein expression level of PRSS3 was tested and compared in primary cells generated from different clinical specimens. (b) Protein expression level of PRSS3 was tested and compared in different commercially available DLBCL cell lines. (c) SUDHL10 cells were treated with PRSS3-shRNA or control-shRNA. The knockdown effectiveness was evaluated by immunoblotting. (d) SUDHL10 cell proliferation curves were plotted according to the MTT assay. (e) OCI-LY3 cells were treated with PRSS3-shRNA or control-shRNA. The knockdown efficiency was evaluated by immunoblotting. (f) OCI-LY3 cell proliferation curves were plotted according to the MTT assay.

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