Research Article

The Association between Serum Total Bile Acid Level and Long-Term Prognosis in Patients with Coronary Chronic Total Occlusion Undergoing Percutaneous Coronary Intervention

Table 1

Characteristics of patients according to TBA levels.

Variables≤3.5 ()3.5-10 ()≥10 () value

Age (years)0.148
Male (%)262 (84.8)209 (84.6)47 (82.5)0.903
BMI (kg/m2)0.791
Smoking (%)153 (49.5)126 (51.0)27 (47.4)0.866
Drinking (%)70 (22.7)51 (20.6)12 (21.1)0.843
Hypertension (%)170 (55.0)133 (53.8)35 (61.4)0.585
Diabetes mellitus (%)112 (36.2)87 (31.5)21 (40.7)0.957
Prior MI (%)98 (31.7)80 (32.4)19 (33.3)0.966
DBP (mmHg)72.0 (66.0, 80.0)71.0 (67.0, 80.0)73.0 (69.5, 80.0)0.516
SBP (mmHg)125.0 (117.0, 138.0)125.0 (116.0, 139.0)130.0 (117.5, 135.0)0.916
Heart rate (bmp)70.0 (66.0, 74.0)70.0 (65.0, 74.0)70.0 (67.0, 74.0)0.201
Stent numbers2.0 (2.0, 3.0)2.0 (2.0, 3.0)2.0 (2.0, 3.0)0.412
Creatinine (mg/dl)68.00 (57.75, 81.50)69.60 (60.02, 79.70)63.00 (57.75, 75.00)0.083
hs-CRP (μg/ml)1.40 (1.20, 1.80)1.40 (1.00, 1.60)1.40 (1.40, 2.25)0.133
Triglyceride (mmol/l)1.41 (1.04, 1.96)1.42 (0.97, 2.19)1.41 (0.85, 2.28)0.987
Cholesterol (mmol/l)3.71 (3.08, 4.30)3.67 (3.07, 4.44)3.43 (2.96, 3.99)0.214
LDL (mmol/l)2.09 (1.63, 2.61)2.09 (1.58, 2.75)1.96 (1.49, 2.40)0.249
HDL (mmol/l)0.91 (0.78, 1.06)0.94 (0.80, 1.09)0.89 (0.77, 1.01)0.323
Albumin (g/l)39.15 (36.70, 41.90)39.40 (37.00, 41.80)38.50 (36.90, 41.50)0.534
Platelets (109/l)184.00 (153.00, 221.50)176.00 (141.75, 225.50)162.00 (135.00,1 99.00)#0.017
LVEF (%)60.00 (45.00, 68.00)58.00 (44.00, 66.00)64.00 (52.00, 67.00)0.054
CK-MB (U/l)12.00 (9.40, 16.00)12.00 (9.16, 15.00)13.10 (9.00, 16.80)0.605
pro-BNP (pg/ml)355.0 (166.0, 1063.0)355.0 (146.0, 1183.0)334.00 (134.50,613.00)0.416
TSH (uIU/ml)1.95 (1.25, 3.20)2.13 (1.31, 3.31)2.12 (1.30, 2.93)0.696
Revascularization (%)221 (71.5)171 (69.2)38 (66.7)0.702
Aspirin (%)231 (74.8)168 (68.0)46 (80.7)0.162
Clopidogrel (%)114 (36.9)100 (40.5)23 (40.4)0.284
Statin (%)192 (62.1)149 (60.3)33 (57.9)0.629
ACEI/ARB (%)93 (30.1)63 (25.5)15 (26.3)0.488
β-Blocker (%)172 (55.7)127 (51.4)29 (50.9)0.370
CCB (%)65 (21.0)57 (23.1)10 (17.5)0.418

BMI: body mass index; MI: myocardial infarction; DBP: diastolic blood pressure; SBP: systolic blood pressure; hs-CRP: high-sensitivity C-reactive protein; LDL: low-density lipoprotein; HDL: high-density lipoprotein; LVEF: left ventricular ejection fraction; CK-MB: creatine kinase isoenzymes MB; pro-BNP: pro-B-type natriuretic peptide; TSH: thyroid-stimulating hormone; ACEI: angiotensin-converting enzyme inhibition; ARB: angiotensin receptor blocker. CCB: calcium channel blocker. Compliance with medication is indicated. “” represents Group 1 vs. Group 3; “#” represents Group 2 vs. Group 3; Group1: ~3.5, Group2: 3.5 ~ 10, Group3: ~10.