Research Article
Construction of a Humanized PBMC-PDX Model to Study the Efficacy of a Bacterial Marker in Lung Cancer Immunotherapy
Figure 4
Establishing PBMCs humanized mice and evaluating the effect of immunotherapy on the model. (a) PBMCs humanized mice. FACS profiles of human CD45+ and CD3+ in NPI mice at the appointed time. (b) Effect of immunotherapy. The survival time decreased after pembrolizumab treatment; . , , and . are used in graphs. Two-sample -test. Statistics on survival days (b). values are significance.
(a) |
(b) |