Circulating ADAMTS13 Levels Are Associated with an Increased Occurrence of Obstructive Sleep Apnea
Table 1
Comparison of demographic and sleep data between OSA patients and controls.
Variables
Controls ()
OSA ()
value
Anthropometric characteristics
Age (years)
0.798
Male, (%)
49 (62.8%)
119 (82.1%)
0.002
BMI (kg/m2)
<0.001
Current smoker, (%)
26 (33.3%)
57 (39.3%)
0.318
Diabetes mellitus, (%)
10 (12.8%)
21 (14.5%)
0.476
Hypertension, (%)
24 (30.7%)
83 (57.2%)
<0.001
Hypercholesterolemia, (%)
8 (10.3%)
24 (16.6%)
0.304
CAD, (%)
13 (16.7%)
69 (47.6%)
<0.001
SBP (mmHg)
120.0 (112.5-134.0)
124.5 (117.0-135.3)
0.027
DBP (mmHg)
70.0 (63.2-83.5)
79.0 (71.0-88.0)
0.011
Sleep data
Neck circumference (cm)
<0.001
AHI (events/h)
2.7 (1.6-3.9)
29.1 (16.7-59.4)
<0.001
ESS
0 (0-7)
9 (5-13)
<0.001
MSaO2 (%)
96.0 (95.0-97.0)
95.0 (93.0-95.2)
<0.001
Lowest SaO2 (%)
92.0 (91.0-93.3)
81.0 (74.0-87.8)
<0.001
CT90% (%)
0 (0-0.15)
2.8 (0.0-17.6)
<0.001
Arousal index (events/h)
4.1 (0.0-9.6)
12.6 (6.7-40.0)
<0.001
Data are presented as or (%), , or median (interquartile range, IQR), unless otherwise stated. OSA: obstructive sleep apnea; BMI: body mass index; CAD: coronary artery disease; SBP: systolic blood pressure; DBP: diastolic blood pressure; AHI: apnea-hypopnea index; ESS: Epworth Sleepiness Scale; MSaO2: mean oxygen saturation; lowest SaO2: lowest oxygen saturation; CT90: percentage of cumulative time with oxygen saturation below 90% during sleep time.
