Research Article

Siglec-15 Silencing Inhibits Cell Proliferation and Promotes Cell Apoptosis by Inhibiting STAT1/STAT3 Signaling in Anaplastic Thyroid Carcinoma

Table 1

Correlation between Siglec-15 expression and clinicopathological characteristics in THCA patients.

CharacteristicsNumberSiglec-15 expression values
Low ()High ()

Type
 FTC167915.8850.001
 PTC26215
 Adenoma1349
 ATC311021
Gender
 Male3819190.0370.848
 Female482325
Age (years)
 ≥653720170.7070.400
 <65492227
Tumor size (cm)
 ≤24326174.6540.031
 >2431627
Lymph nodes metastasis
 No6028320.3740.541
 Yes261412
Distant metastasis
 No42291313.420<0.001
 Yes441331

Note: THCA: thyroid cancer; FTC: follicular thyroid carcinoma; PTC: papillary thyroid carcinoma; ATC: anaplastic thyroid cancer. .