LTB4 Promotes Acute Lung Injury via Upregulating the PLC<i>ε</i>-1/TLR4/NF-<i>κ</i>B Pathway in One-Lung Ventilation

<div>Inhibiting LTB4 reduces PLC<i>ε</i>-1 expression. (a–c) qRT-PCR validated expression of LTA4H, BLT1, and PLC<i>ε</i>-1 in control, OLV, and bestatin-treated rats. (d, e) Western blot was performed to examine expression of LTA4H, BLT1, and PLC<i>ε</i>-1 in control, OLV, and bestatin-treated rats. 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Disease Markers

fig4

Figure 4

Figure 4: LTB4 Promotes Acute Lung Injury via Upregulating the PLC<i>ε</i>-1/TLR4/NF-<i>κ</i>B Pathway in One-Lung Ventilation 

Disease Markers

LTB4 Promotes Acute Lung Injury via Upregulating the PLCε-1/TLR4/NF-κB Pathway in One-Lung Ventilation

Figure 4