Identification of Novel Diagnostic Biomarkers in Prostate Adenocarcinoma Based on the Stromal-Immune Score and Analysis of the WGCNA and ceRNA Network

Figure 2

Weighted coexpression network-related graphics. (a, b) Determine the soft thresholding parameter in the lncRNA/mRNA (a) and the miRNA (b) WGCNA. The scale-free fit index and mean connectivity of various soft threshold parameters () are shown on the left and right picture, respectively. (c, d) Cluster dendrogram of lncRNA/mRNA (c) and miRNA (d) coexpression modules identified by value. Colors are associated with coexpression modules (color gray represents no lncRNA/mRNA or miRNA assigned). (e, f) The association between different lncRNA and mRNA modules (e), miRNA modules (f), and the clinical characteristics of prostate cancer patients. The numbers listed on the right to the heatmap are the number of lncRNA, mRNA, and ncRNA in the lncRNA and mRNA module or the number of miRNAs in the miRNA module. lncRNA: long-chain noncoding RNA; mRNA: messenger RNA; miRNA: microRNA; WGCNA: weighted gene coexpression network analysis; ncRNA: noncoding RNA.

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