ATAD2 Upregulation Promotes Tumor Growth and Angiogenesis in Endometrial Cancer and Is Associated with Its Immune Infiltration

Figure 5

Upregulation of ATAD2 promotes tumor growth and angiogenesis. (a) Transplant tumor growth in mice after injection of ATAD2 overexpression, knockdown, and control of endometrial cancer cells. (b–d) Expression of ATAD2, VEGF, and MVD in knockdown ATAD2 tumors. (e) Mouse transplant tumor growth curve. (f) Immunohistochemical images corresponding to knockdown of ATAD2 (magnification, 200x). (g) The picture of immunohistochemistry of transplanted tumor when ATAD2 was overexpressed above (magnification, 200x). (h–j) Overexpression of ATAD2 increases the expression of VEGF and MVD in transplanted tumor models.

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