Interferon Regulatory Factor Family Genes: At the Crossroads between Immunity and Head and Neck Squamous Carcinoma

Table 1

The correlation among IRF family genes in HNSC, analyzed by Pearson correlation coefficient analysis.

IRF family genes	IRF1		IRF2		IRF3		IRF4		IRF5		IRF6		IRF7		IRF8		IRF9
	value	value	value	value	value	value	value	value	value	value	value	value	value	value	value	value	value	value
IRF1	1.000	<0.001	0.493	<0.001	0.274	<0.001	0.451	<0.001	0.223	<0.001	0.089	0.046	0.471	<0.001	0.632	<0.001	0.414	<0.001
IRF2	0.493	<0.001	1.000	<0.001	0.005	0.916	0.389	<0.001	0.371	<0.001	0.316	<0.001	0.057	0.204	0.436	<0.001	0.324	<0.001
IRF3	0.274	<0.001	0.005	0.916	1.000	<0.001	-0.008	0.859	-0.022	0.625	-0.045	0.314	0.273	<0.001	0.103	0.021	0.253	<0.001
IRF4	0.451	<0.001	0.389	<0.001	-0.008	0.859	1.000	<0.001	0.209	<0.001	-0.074	0.098	0.153	<0.001	0.767	<0.001	0.220	<0.001
IRF5	0.223	<0.001	0.371	<0.001	-0.022	0.625	0.209	<0.001	1.000	<0.001	0.205	<0.001	-0.107	0.017	0.307	<0.001	0.100	0.025
IRF6	0.089	0.046	0.316	<0.001	-0.045	0.314	-0.074	0.098	0.205	<0.001	1.000	<0.001	-0.060	0.176	-0.124	0.005	0.124	0.005
IRF7	0.471	<0.001	0.057	0.204	0.273	<0.001	0.153	<0.001	-0.107	0.017	-0.060	0.176	1.000	<0.001	0.305	<0.001	0.340	<0.001
IRF8	0.632	<0.001	0.436	<0.001	0.103	0.021	0.767	<0.001	0.307	<0.001	-0.124	0.005	0.305	<0.001	1.000	<0.001	0.250	<0.001
IRF9	0.414	<0.001	0.324	<0.001	0.253	<0.001	0.220	<0.001	0.100	0.025	0.124	0.005	0.340	<0.001	0.250	<0.001	1.000	<0.001