UPLC/Q-TOF MS-Based Urine Metabonomics Study to Identify Diffuse Axonal Injury Biomarkers in Rat

Figure 1

Brian tissues collected in injury and control groups were subjected to histopathological analysis. (a, e) 1 d control; (b, f) 3 d control; (c, g) 1 d; (d, h) 3 d groups. Tissues were examined after being stained with (a–d) HE and (e–h) Bielschowsky silver. This work collected each specimen in the corpus callosum. Axons of injury groups exhibited swellings and disconnection with ARBs to varying degrees (c, d, g, h; arrows), while the control group did not exhibit any abnormality in axons (a, b, e, f).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)