Research Article
Identification of Novel Subtypes in Lung Adenocarcinoma: Evidence from Gene Set Variation Analysis in Tumor and Adjacent Nontumor Samples
Table 1
The correlation between clinical characteristics and subtypes.
| | Total | C1 () | C2 () | C3 () | value |
| | Gender (%) | | | | | 0.0039 | | Female | 270 (54%) | 74 (43.79%) | 117 (57.92%) | 79 (61.24%) | | | Male | 230 (46%) | 95 (56.21%) | 85 (42.08%) | 50 (38.76%) | | | Age (%) | | | | | 0.0003 | | <60 | 146 (29.2%) | 65 (38.46%) | 59 (29.21%) | 22 (17.05%) | | | > =60 | 354 (70.8%) | 104 (61.54%) | 143 (70.79%) | 107 (82.95%) | | | TNM staging (%) | | | | | 0.0103 | | I | 268 (53.6%) | 73 (43.2%) | 112 (55.45%) | 83 (64.34%) | | | II | 119 (23.8%) | 46 (27.22%) | 51 (25.25%) | 22 (17.05%) | | | III | 80 (16%) | 36 (21.3%) | 30 (14.85%) | 14 (10.85%) | | | IV | 25 (5%) | 12 (7.1%) | 7 (3.47%) | 6 (4.65%) | | | Unknown | 8 (1.6%) | 2 (1.18%) | 2 (0.99%) | 4 (3.1%) | | | T staging (%) | | | | | 0.0001 | | T1 | 167 (33.4%) | 38 (22.49%) | 67 (33.17%) | 62 (48.06%) | | | T2 | 267 (53.4%) | 103 (60.95%) | 118 (58.42%) | 46 (35.66%) | | | T3 | 45 (9%) | 20 (11.83%) | 12 (5.94%) | 13 (10.08%) | | | T4 | 18 (3.6%) | 7 (4.14%) | 5 (2.48%) | 6 (4.65%) | | | Unknown | 3 (0.6%) | 1 (0.59%) | 0 (0%) | 2 (1.55%) | | | M staging (%) | | | | | 0.0765 | | M0 | 332 (66.4%) | 119 (70.41%) | 135 (66.83%) | 78 (60.47%) | | | M1 | 24 (4.8%) | 12 (7.1%) | 7 (3.47%) | 5 (3.88%) | | | Unknown | 144 (28.8%) | 38 (22.49%) | 60 (29.7%) | 46 (35.66%) | | | N staging (%) | | | | | 0.0012 | | N0 | 324 (64.8%) | 96 (56.8%) | 129 (63.86%) | 99 (76.74%) | | | N1 | 94 (18.8%) | 38 (22.49%) | 41 (20.3%) | 15 (11.63%) | | | N2 | 69 (13.8%) | 33 (19.53%) | 27 (13.37%) | 9 (6.98%) | | | N3 | 2 (0.4%) | 0 (0%) | 2 (0.99%) | 0 (0%) | | | Unknown | 11 (2.2%) | 2 (1.18%) | 3 (1.49%) | 6 (4.65%) | |
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