G Protein-Coupled Receptor Kinase 4 Is a Novel Prognostic Factor in Hepatocellular Carcinoma

Table 1

Correlation between GRK4 expression and clinicopathological features in HCC 325 patients.

Features	Case no. ()	GRK4 expression			value
		High (, %)	Low (, %)
Sex				0.44	0.559
Female	60	21 (16.7)	39 (19.6)
Male	265	105 (83.3)	160 (80.4)
Age (years)				2.03	0.172
<50	158	55(43.7)	103(51.8)
≥50	167	71 (56.3)	96 (48.2)
Histological grade				81.357	<0.001
I	60	54 (42.9)	6 (3.0)
II-IV	265	72 (57.1)	193 (97)
T stage				21.436	<0.001
T1-T2	225	106 (84.1)	119 (59.8)
T3-T4	100	20 (15.9)	80 (40.2)
N stage				4.061	0.044
N0	305	123 (97.6)	182 (91.5)
N1	20	3 (2.4)	17 (8.5)
M stage				1.689	0.194
M0	313	124 (98.4)	189 (95)
M1	12	2 (1.6)	10 (5)
TNM stage				18.964	<0.001
I-II	208	99 (78.6)	109 (54.8)
III-IV	117	27 (21.4)	90 (45.2)