Research Article

Circulating miRNAs as Epigenetic Mediators of Periodontitis and Preeclampsia Association

Table 4

Overrepresented GO terms among shared DEmiRNA associated with periodontitis and preeclampsia.

Subcategory value adjustedObserved/expected ratio

GO0045741 positive regulation of epidermal growth factor-activated receptor activity0.0315.35
GO0051208 sequestering of calcium ion0.0113.59
GO0016272 prefoldin complex0.0312.42
GO0035371 microtubule plus end0.0110.87
GO0030877 beta catenin destruction complex0.049.66
GO0009798 axis specification0.049.32
GO0007064 mitotic sister chromatid cohesion0.039.06
GO0030858 positive regulation of epithelial cell differentiation0.049.00
GO0034383 low-density lipoprotein particle clearance0.049.00
GO0070062 extracellular vesicular exosome0.049.00
GO0071837 hmg box domain binding0.038.81
GO0034236 protein kinase a catalytic subunit binding0.058.42
GO0044295 axonal growth cone0.058.42
GO0060770 negative regulation of epithelial cell proliferation involved in prostate gland development0.058.42
GO0051010 microtubule plus end binding0.038.36
GO0046716 muscle cell homeostasis0.047.58
GO0046627 negative regulation of insulin receptor signaling pathway0.027.53
GO0071277 cellular response to calcium ion0.047.41
GO0000718 nucleotide excision repair DNA damage removal0.047.25
GO0007091 mitotic metaphase anaphase transition0.047.09
GO0046676 negative regulation of insulin secretion0.046.39
GO0042157 lipoprotein metabolic process0.046.27
GO0007052 mitotic spindle organization0.055.72
GO0070830 tight junction assembly0.055.72
GO0005881 cytoplasmic microtubule0.025.64
GO0060041 retina development in camera type eye0.045.51
GO0007409 axonogenesis0.025.31
GO0048009 insulin-like growth factor receptor signaling pathway0.044.89
GO0001102 RNA polymerase ii activating transcription factor binding0.044.77
GO0071230 cellular response to amino acid stimulus0.044.66
GO0000724 double-strand break repair via homologous recombination0.044.55
GO0000776 kinetochore0.034.35
GO0090090 negative regulation of canonical Wnt receptor signaling pathway0.054.30
GO0032869 cellular response to insulin stimulus0.044.15
GO0008083 growth factor activity0.033.75
GO0016568 chromatin modification0.053.46
GO0044255 cellular lipid metabolic process0.053.43
GO0030335 positive regulation of cell migration0.043.09
GO0008286 insulin receptor signaling pathway0.042.87
GO0046777 protein autophosphorylation0.042.87
GO0007155 cell adhesion0.052.82
GO0005794 Golgi apparatus0.042.40
GO0008134 transcription factor binding0.042.39
GO0005887 integral to plasma membrane0.042.37