Comprehensive Analysis of DNA Methylation and Transcriptome to Identify PD-1-Negative Prognostic Methylated Signature in Endometrial Carcinoma

Figure 6

Molecular docking of resveratrol and CLEC14A. (a) 3D structure of CLEC14A protein predicted in SwissModel. (b) The Ramachandran plot of CLEC14A protein structure, and red, yellow, and white were the conformational permissible, permissible, and nonpermissible regions, respectively. (c) The change curve of the RMSD value of protein skeleton in the process of 100 ns molecular dynamics. (d) Two-dimensional interaction diagram of resveratrol and CLEC14A protein, the green dotted line represented the hydrogen bond, and the pink dotted line represented the hydrophobic interaction. (e) The 3-dimensional docking results of resveratrol and CLEC14A protein, the yellow structure represented the ligand, and the heteroatoms on it were shown as elements. The steel blue structure was an amino acid residue, and the heteroatoms on it were also shown as elements.

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