Comprehensive Analysis of DNA Methylation and Transcriptome to Identify PD-1-Negative Prognostic Methylated Signature in Endometrial Carcinoma

Figure 8

Verification of the 2-gene signature. (a) The risk score distribution, survival status scatter diagram, and expression heat map of 2 genes in the verification set. (b) Kaplan–Meier curves based on the log-rank test were created to visualize the prognostic value of 2-gene signature in the verification set. (c) The ROC curve over time in the validation set. (d) The risk score of the samples, distribution of survival time and state, and the expression heat map of ELFN1-AS1 and ZNF132 in the PD-1-negative cohort. (e) Kaplan–Meier curves based on the log-rank test were generated to visualize the prognostic value of the 2-gene signature in the entire PD-1-negative cohort. (f) ROC curve with time in PD-1-negative cohort.

(a)

(b)

(c)

(d)

(e)

(f)