Research Article
The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy
Table 2
Main clinical characteristics of lung cancer patients and prognosis analysis.
| | Characteristics | Patients (%) | Death (%) | MST-OS (year) | P | MST-PFS (year) | |
| | Total | 593 | 416 | 4.04 | | 3.49 | | | Age (years) | | | | | | | | ≤60 | 412 (69.4) | 280 (67.3) | 4.38 | 0.822 | 3.43 | 0.692 | | >60 | 181 (30.5) | 136 (32.6) | 4.65 | | 3.75 | | | Sex | | | | | | | | Male | 468 (78.9) | 335 (80.5) | 4.38 | 0.082 | 3.45 | 0.449 | | Female | 125 (21.1) | 80 (19.2) | 4.53 | | 3.43 | | | Smoking status | | | | Nonsmoker | 227 (38.3) | 149 (35.8) | 4.53 | 0.132 | 3.28 | 0.411 | | Smoker | 366 (61.7) | 265 (63.7) | 4.36 | | 3.45 | | | Histology | | | | | | | | NSCLC | 449 (75.7) | 359 (76.4) | 4.68 | 0.361 | 4.44 | 0.093 | | SCLC | 122 (20.6) | 93 (8.3) | 4.42 | | 4.01 | | | Others | 22 (3.7) | 18 (3.8) | 3.81 | | 4.10 | | | Stage | | | | | | | | I/II/LD | 68 (11.5) | 44 (10.6) | 4.62 | 0.345 | 4.30 | 0.558 | | III/IV/ED | 519 (87.5) | 363 (87.3) | 4.31 | | 3.41 | |
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NSCLC: non-small-cell lung cancer; SCLC: small cell lung cancer; LUSC: squamous cell carcinoma; LUAD: adenocarcinoma.
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