Research Article

The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy

Table 4

Stratification analyses of association between polymorphisms and PFS or OS in lung cancer patients.

PFS/OSPolymorphismGenotypeSubgroupAdditiveDominantRecessive
OR (95% CI)OR (95% CI)OR (95% CI)

PFSrs17292622RPA1TNM21.56 (0.98-2.48)0.0601.89 (1.06-3.38)0.0321.34 (0.49-3.67)0.563
OSrs2228006PMS2≤600.31 (0.11-0.87)0.0270.31 (0.11-0.87)0.027
rs1062372PMS2LUAD0.49 (0.20-1.20)0.1210.58 (0.18-1.81)0.3470.16 (0.03-0.95)0.043

Additive model: comparison between minor allele subjects and major allele subjects. Dominant model: comparison between minor allele carriers and major homozygous subjects. Recessive model: comparison between major allele carriers and minor homozygous subjects. OR: odds ratio; CI: confidence interval. .