Disease Markers / 2022 / Article / Tab 8 / Research Article
Prognostic Markers in Hospitalized COVID-19 Patients: The Role of IP-10 and C-Reactive Protein Table 8 Routine laboratory findings and multiplex quantifications after 7 days of hospitalization in patients who had a faster clinical recovery (discharged or reaching
for at least 24 hours within 14 days) vs. all the other patients. Data are expressed as median (IQR). Bold text highlights the statistically significant results.
Laboratory findings after 7 days ( ) Faster clinical recovery ( ) All other patients ( ) valueHemoglobin (g/dL) 13.5 [12.5-15.0] 13.6 [12.3-14.2] 0.9946 0.3199 RDW-CV (%) 13.0 [12.5-13.6] 13.4 [12.9-13.9] -2.1164 0.0343 White blood cells ( ) 9.40 [7.22-10.91] 10.36 [8.32-12.13] -1.7866 0.0740 Neutrophils ( ) 6.79 [5.59-8.37] 8.99 [7.22-10.55] -3.3804 0.0007 Eosinophils ( ) 0.02 [0.01-0.08] 0.02 [0.00-0.04] 1.3076 0.1910 Lymphocytes ( ) 1.50 [0.85-1.95] 0.62 [0.39-1.03] 4.4788 0.0001 Neutrophil/lymphocyte ratio 4.82 [3.16-8.98] 13.19 [7.74-32.29] -4.8490 0.0001 Platelets ( ) 348 [303-417] 302 [260-371] 2.2241 0.0261 ALT (U/L) 63 [38-112] 41 [27-69] 2.4130 0.0158 AST (U/L) 30 [24-45] 30 [23-40] 0.5323 0.5945 Bilirubin (mg/dL) 0.6 [0.5-0.9] 0.7 [0.6-0.9] -0.3411 0.7330 Creatinine (mg/dL) 0.72 [0.62-0.85] 0.73 [0.55-0.83] 0.5298 0.5963 Glomerular filtration rate (mL/min) 98 [88-107] 91 [69-102] 1.9951 0.0460 CRP (mg/dL) 0.8 [0.3-1.9] 3.7 [2.3-7.8] -6.1875 <0.0001 LDH (U/L) 551 [449-650] 645 [561-819] -3.3632 0.0008 Erythrocyte sedimentation rate (mm/h) 25 [16-43] 50 [32-63] -3.1074 0.0019 Troponin I (ng/mL) 4 [2-7] 6 [3-22] -2.2200 0.0264 Ferritin (ng/mL) 751 [452-998] 793 [520-1346] -1.2909 0.1968 D-dimer (μ g/L) 903 [567-1438] 1755 [1132-2639] -3.5792 0.0003 Albumin (g/dL) 3.6 [3.4-3.8] 3.4 [3.2-3.7] 1.9968 0.0458 Eotaxin (pg/mL) 5.06 [3.59-7.92] 4.26 [3.68-6.09] 0.8166 0.4142 FGF (pg/mL) 19.63 [10.82-28.33] 20.40 [12.68-28.66] -0.3791 0.7046 G-CSF (pg/mL) 78.28 [59.83-98.47] 93.75 [77.86-156.42] -2.5911 0.0096 GM-CSF (pg/mL) 0.00 [0.00-0.00] 0.00 [0.00-0.00] 1.7318 0.0833 IFN-γ (pg/mL) 6.14 [3.82-9.72] 9.57 [6.61-13.09] -2.8483 0.0044 IL-1β (pg/mL) 0.38 [0.00-1.09] 0.59 [0.00-1.43] -0.3944 0.6933 IL1-RA (pg/mL) 0.00 [0.00-117.10] 0.00 [0.00-168.65] -1.1670 0.2432 IL-2 (pg/mL) 0.79 [0.00-2.77] 2.01 [0.00-4.22] -0.5259 0.5989 IL-4 (pg/mL) 0.58 [0.14-0.92] 0.68 [0.00-1.10] -0.2517 0.8013 IL-5 (pg/mL) 0.00 [0.00-72.05] 0.00 [0.00-72.05] 0.2073 0.8357 IL-6 (pg/mL) 2.13 [0.00-6.63] 9.60 [5.39-17.71] -4.3785 0.0001 IL-7 (pg/mL) 1.93 [0.00-18.09] 9.00 [0.91-22.56] -1.4369 0.1507 IL-8 (pg/mL) 9.42 [6.49-14.56] 21.19 [11.85-28.97] -4.0087 0.0001 IL-9 (pg/mL) 460.38 [403.05-520.05] 460.82 [368.17-516.36] 0.1341 0.8933 IL-10 (pg/mL) 0.97 [0.00-3.63] 2.05 [0.10-4.88] -1.3278 0.1842 IL-12 (pg/mL) 1.34 [0.00-3.96] 1.56 [0.00-3.96] 0.0000 1.0000 IL-13 (pg/mL) 0.00 [0.00-0.79] 0.00 [0.00-0.35] 0.6089 0.5426 IL-15 (pg/mL) 0.00 [0.00-172.77] 0.00 [0.00-84.08] 0.6610 0.5029 IL-17 (pg/mL) 4.73 [3.65-6.49] 4.94 [3.42-6.37] -0.1294 0.8970 IP-10 (pg/mL) 668.26 [377.20-1164.56] 1897.80 [1022.41-4465.42] -4.4249 0.0001 MCP-1 (pg/mL) 59.34 [38.81-100.05] 106.19 [60.87-359.83] -3.2373 0.0012 MIP-1α (pg/mL) 2.23 [1.51-2.69] 3.25 [2.40-4.36] -3.5158 0.0004 MIP-1β (pg/mL) 234.90 [207.93-256.98] 230.67 [181.26-246.32] 0.9721 0.3310 PDGF (pg/mL) 2270.91 [1463.58-3558.49] 1918.40 [929.93-3491.39] 0.9099 0.3629 RANTES (pg/mL) 7255.70 [4279.12-12430.58] 7635.33 [2738.21-10391.71] 0.5172 0.6050 TNF-α (pg/mL) 23.77 [16.92-28.63] 19.89 [15.42-25.97] 1.1116 0.2663 VEGF (pg/mL) 105.40 [0.00-188.97] 119.46 [0.00-264.76] -1.0418 0.2975