Hypermagnesaemia, but Not Hypomagnesaemia, Is a Predictor of Inpatient Mortality in Critically Ill Children with Sepsis
Table 1
Baseline characteristics.
Variable
Hypomagnesemia ()
Normomagnesemia ()
Hypermagnesemia ()
value 1
value 2
Age, months
47 (22, 90)
28.3 (14.6, 66.9)
18.7 (12.1, 45.6)
<0.001
0.027
Male, (%)
121 (49.2)
353 (53.0)
35 (56.5)
0.306
0.603
Laboratory data
APTT, s
29.7 (26.6, 32.9)
30.0 (26.9, 34.6)
31.5 (25.9, 38.0)
0.124
0.547
Ionized calcium, mmol/L
1.21 (1.13, 1.25)
1.22 (1.14, 1.28)
1.22 (1.18, 1.32)
0.010
0.228
Potassium, mmol/L
3.6 (3.3, 4.0)
3.7 (3.3, 4.0)
3.9 (3.5, 4.3)
0.037
0.010
Lactate, mmol/L
2 (1.3, 3.1)
1.8 (1.3, 2.8)
2.2 (1.4, 3.6)
0.244
0.061
Sodium, mmol/L
137 (135, 139)
137 (135, 140)
138 (135, 141)
0.059
0.305
PH
7.36 (7.31, 7.40)
7.37 (7.33, 7.42)
7.35 (7.25, 7.40)
0.005
0.015
Platelet, 109/L
271 (186, 387)
245 (159, 348)
263 (169, 397)
0.003
0.213
White blood cell, 109/L
12.7 (7.8, 17.6)
11.0 (6.7, 16.1)
12.0 (5.7, 16.5)
0.053
0.730
Comorbidities, (%)
Acute kidney injury
25 (10.2)
112 (16.8)
20 (32.3)
0.013
0.003
Anemia
188 (76.4)
517 (77.6)
45 (72.6)
0.700
0.365
Congenital heart disease
37 (15.0)
256 (38.4)
12 (19.4)
<0.001
0.003
Diabetic ketoacidosis
22 (8.9)
94 (14.1)
13 (21.0)
0.038
0.145
Liver dysfunction
40 (16.3)
74 (11.1)
16 (25.8)
0.037
0.001
Malignancy
33 (13.4)
15 (2.3)
1 (1.6)
<0.001
0.743
Clinical outcome
Hospital LOS (day)
12.9 (8.8, 21)
13 (8.9, 19.6)
13.7 (7.6, 23.1)
0.568
0.678
Hospital mortality, (%)
5 (2.0)
16 (2.4)
9 (14.5)
0.741
<0.001
value 1 represents the value for the comparison between the group of hypomagnesemia and the group of normomagnesemia. value 2 represents the value for the comparison between the group of hypermagnesemia and the group of normomagnesemia. APTT: activated partial thromboplastin time; LOS: length of stay.