Research Article

Hypermagnesaemia, but Not Hypomagnesaemia, Is a Predictor of Inpatient Mortality in Critically Ill Children with Sepsis

Table 1

Baseline characteristics.

VariableHypomagnesemia
()
Normomagnesemia
()
Hypermagnesemia
()
value 1  value 2 

Age, months47 (22, 90)28.3 (14.6, 66.9)18.7 (12.1, 45.6)<0.0010.027
Male, (%)121 (49.2)353 (53.0)35 (56.5)0.3060.603
Laboratory data
 APTT, s29.7 (26.6, 32.9)30.0 (26.9, 34.6)31.5 (25.9, 38.0)0.1240.547
 Ionized calcium, mmol/L1.21 (1.13, 1.25)1.22 (1.14, 1.28)1.22 (1.18, 1.32)0.0100.228
 Potassium, mmol/L3.6 (3.3, 4.0)3.7 (3.3, 4.0)3.9 (3.5, 4.3)0.0370.010
 Lactate, mmol/L2 (1.3, 3.1)1.8 (1.3, 2.8)2.2 (1.4, 3.6)0.2440.061
 Sodium, mmol/L137 (135, 139)137 (135, 140)138 (135, 141)0.0590.305
 PH7.36 (7.31, 7.40)7.37 (7.33, 7.42)7.35 (7.25, 7.40)0.0050.015
 Platelet, 109/L271 (186, 387)245 (159, 348)263 (169, 397)0.0030.213
 White blood cell, 109/L12.7 (7.8, 17.6)11.0 (6.7, 16.1)12.0 (5.7, 16.5)0.0530.730
Comorbidities, (%)
 Acute kidney injury25 (10.2)112 (16.8)20 (32.3)0.0130.003
 Anemia188 (76.4)517 (77.6)45 (72.6)0.7000.365
 Congenital heart disease37 (15.0)256 (38.4)12 (19.4)<0.0010.003
 Diabetic ketoacidosis22 (8.9)94 (14.1)13 (21.0)0.0380.145
 Liver dysfunction40 (16.3)74 (11.1)16 (25.8)0.0370.001
 Malignancy33 (13.4)15 (2.3)1 (1.6)<0.0010.743
Clinical outcome
 Hospital LOS (day)12.9 (8.8, 21)13 (8.9, 19.6)13.7 (7.6, 23.1)0.5680.678
Hospital mortality, (%)5 (2.0)16 (2.4)9 (14.5)0.741<0.001

value 1 represents the value for the comparison between the group of hypomagnesemia and the group of normomagnesemia. value 2 represents the value for the comparison between the group of hypermagnesemia and the group of normomagnesemia. APTT: activated partial thromboplastin time; LOS: length of stay.