GSK3B Overexpression Alleviates Posttraumatic Osteoarthritis in Mice by Promoting DNMT1-Mediated Hypermethylation of NR4A3 Promoter

<div>GSK3B protein is downregulated in articular cartilage of patients with posttraumatic osteoarthritis. We collected 18 cartilage tissues from amputation patients as a normal control group and 25 cartilage tissues from PTOA patients. Then, western blotting was used to detect the expression of GSK3B protein. 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Disease Markers

fig1

Figure 1

Figure 1: GSK3B Overexpression Alleviates Posttraumatic Osteoarthritis in Mice by Promoting DNMT1-Mediated Hypermethylation of NR4A3 Promoter 