Predictive Value of Monocyte Chemoattractant Protein-1 in the Development of Diastolic Dysfunction in Patients with Psoriatic Arthritis

Table 1

Comparison of echocardiographic parameters in patients with PsA classified into groups with respect to the cut-off MCP-1 concentration (347.6 pg/mL).

	Patients with serum MCP-1		value
	≤347.6 pg/mL (); Median (25^th; 75^th percentiles)	>347.6 pg/mL (); Median (25^th; 75^th percentiles)
E wave (m/s)	0.7 (0.62; 0.78)	0.67 (0.63; 0.71)	0.452
A wave (m/s)	0.62 (0.56; 0.75)	0.99 (0.86; 1.08)	0.000005
E/A ratio	1.11(0.78; 1.25)	0.68 (0.63; 0.77)	0.000002
LAVI (ml/m^2)	25.25 (22.92; 29.93)	26.9 (21.99; 29.32)	0.844
TR velocity (m/s)	1.99 (1.57; 2.45)	2.01 (1.76; 2.46)	0.747
E (m/s)	0.076 (0.066; 0.08)	0.05 (0.049; 0.063)	0.003
E/E ratio	9 (8.5; 10.2)	12.98 (10.36; 13.5)	0.00005
SA (%)	27.6 (25.44; 33.4)	23.5 (19.9; 25.04)	0.0066
Sr E (1/s)	-1.22 (-1.61; -0.92)	-1.02 (-1.31; -0.78)	0.228
Sr A (1/s)	-1.41 (-1.65; -1.21)	-1.75 (-1.8; -1.3)	0.09
EF (%)	55 (55; 60)	55 (54; 60)	0.46
GLS (%)	-21(-22.6; -19.7)	-20.3 (-21.8; -19)	0.37

MCP-1: Monocyte Chemoattractant Protein-1; E: early peak diastolic mitral inflow velocity; A: late peak diastolic mitral inflow velocity; LAVI: left atrial volume indexed to the body surface area; TR: maximal velocity of tricuspid regurgitation; E: early peak diastolic displacement of the mitral septal annulus; SA: peak systolic left atrial reservoir strain; Sr E: peak strain rate of left atrium conduit phase; SrA: peak strain rate of left atrium contractile phase; EF: ejection fraction; GLS: global longitudinal strain. Level of value with statistical significance, Mann–Whitney test.