Ferroptosis-Specific Inhibitor Ferrostatin-1 Relieves H₂O₂-Induced Redox Imbalance in Primary Cardiomyocytes through the Nrf2/ARE Pathway

Figure 1

Effects of H₂O₂ and ferrostatin-1 on the survival rate of primary cardiomyocytes. (a) The effect of H₂O₂ on cell viability was detected by MTT (“” indicates statistical difference from the 0 μM H₂O₂ group, ; “” indicates statistical difference from the 0 μM H₂O₂ group, ). (b) The effect of ferrostatin-1 on cell viability was detected by MTT. (c) The effect of ferrostatin-1 on H₂O₂-induced cell viability was detected by MTT. (d) LDH activity was detected by kit (“” indicates statistical difference from the control group, ; “#” indicates statistical difference from the H₂O₂ group, ; “” indicates statistical difference from the H₂O₂ group, ).

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