Prognostic Value of Combination of Controlling Nutritional Status and Tumor Marker in Patients with Radical Non-Small-Cell Lung Cancer

Table 3

The Cox regression of overall patients.

Clinicopathological features
	Univariate analysis		Multivariate analysis
	HR (95% CI)		HR (95% CI)
Sex		0.111
Male	1
Female	0.757 (0.537-1.066)
Age	0.994 (0.976-1.014)	0.566
BMI	0.954 (0.907-1.002)	0.061
SCC	1.059 (1.004-1.117)	0.034	1.015 (0.952-1.081)	0.655
CEA	1.000 (0.997-1.004)	0.811
NSE	0.999 (0.995-1.004)	0.786
Smoking history		0.513
No	1
Yes	1.117 (0.802-1.555)
Tumor location		0.484
Left lung	1
Right lung	1.130 (0.803-1.589)
Histological type		0.014		0.004
Squamous cell carcinoma	1		1
Adenocarcinoma	1.230 (0.845-1.791)	0.280	1.856 (1.211-2.843)	0.005
Others	2.558 (1.364-4.797)	0.003	2.513 (1.316-4.801)	0.005
pTNM		<0.001		<0.001
I	1		1
II	2.806 (1.771-4.445)	<0.001	2.614 (1.619-4.222)	<0.001
III	4.036 (2.757-5.907)	<0.001	3.248 (2.183-4.834)	<0.001
T-CONUT		<0.001		<0.001
0	1		1
1	2.749 (1.389-5.443)	0.004	2.720 (1.352-5.471)	0.005
2	3.254 (1.823-5.808)	<0.001	3.252 (1.800-5.874)	<0.001
3	7.204 (3.948-13.145)	<0.001	4.716 (2.470-9.003)	<0.001
PNI		0.002		0.336
≥52.48	1		1
<52.48	1.744 (1.219-2.495)		1.243 (0.798-1.938)
SIS		0.003		0.466
0	1		1
1	1.746 (1.167-2.612)	0.007	1.315 (0.840-2.057)	0.231
2	2.175 (1.374-3.442)	0.001	1.338 (0.761-2.353)	0.311