Research Article
LIN28B Polymorphisms Confer a Higher Postoperative Recurrence Risk in Reproductive-Age Women with Endometrial Polyps
Table 3
Stratification analysis of LIN28B rs369065 polymorphism by selected variables in recurrent and nonrecurrent patients.
| | Recurrence () | Nonrecurrence () | Adjusted HR (95% CI)a | | | CC/TC | TT | CC/CT | TT | | (%) | (%) | (%) | (%) |
| | Age (years) | | | | | | | | <33 | 13 (56.5) | 10 (43.5) | 121 (65.8) | 63 (34.2) | 1.300 (0.559-3.022) | 0.542 | | ≥33 | 8 (38.1) | 13 (61.9) | 87 (70.7) | 36 (29.3) | 2.597 (1.037-6.505) | 0.042 | | Gravidities | | | | | | | | 0 | 7 (43.8) | 9 (56.2) | 78 (60.9) | 48 (39.1) | 1.565 (0.570-4.299) | 0.385 | | 1 | 6 (50.0) | 6 (50.0) | 61 (75.3) | 20 (24.7) | 1.886 (0.556-6.402) | 0.309 | | ≥2 | 8 (50.0) | 8 (50.0) | 69 (69.0) | 31 (31.0) | 1.914 (0.708-5.173) | 0.201 | | Hemoglobin (g/L) | | | | | | | | <126 | 14 (31.82) | 14 (31.82) | 95 (30.94) | 51 (16.61) | 1.837 (0.850-3.973) | 0.122 | | ≥126 | 7 (15.91) | 9 (20.45) | 113 (36.81) | 48 (15.64) | 1.862 (0.657-5.275) | 0.242 | | Number of polyps | | | | | | | | Single polyp | 10 (47.6) | 11 (52.4) | 139 (70.9) | 57 (29.1) | 2.545 (1.059-6.113) | 0.037 | | Multiple polyps | 11 (47.8) | 12 (52.2) | 69 (62.2) | 42 (37.8) | 1.570 (0.683-3.611) | 0.288 | | Diameter of polyp (cm) | | | | | | | | <1.2 | 18 (47.4) | 20 (52.6) | 170 (69.4) | 85 (30.6) | 2.708 (1.042-7.043) | 0.041 | | ≥1.2 | 3 (50.0) | 3 (50.0) | 38 (73.1) | 14 (26.9) | 1.458 (0.672-3.165) | 0.340 | | Endometrial thickness (cm) | | | | | | | | <0.9 | 10 (45.5) | 12 (54.5) | 102 (66.7) | 51 (33.3) | 2.189 (0.920-5.209) | 0.077 | | ≥0.9 | 11 (50.0) | 11 (50.0) | 106 (68.8) | 48 (31.2) | 1.774 (0.750-4.200) | 0.192 |
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HR: hazard ratio. aAdjusted age, gravidities, menarche age, number and size of polyps, and endometrial thickness.
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