Single-Cell RNA-seq Analysis Reveals Dysregulated Cell-Cell Interactions in a Tumor Microenvironment Related to HCC Development

Figure 6

Construction of the prognosis model based on the CCE genes in TME of HCC. (a) The hazard ratio of the genes in the prognosis model. (b) Kaplan-Meier estimates of OS of HCC patients in TCGA as the training datasets based on the 7-gene signature; patients were divided into two risk group according to median risk score. (c) The receiver operating characteristic (ROC) curve for OS survival predictions for the signature in training set. (d) Kaplan-Meier estimates of OS of HCC patients in tumor stage I&II in TCGA based on the signature. (e) Kaplan-Meier estimates of OS of HCC patients in tumor stage III&IV in TCGA based on the signature. (f) Kaplan-Meier estimates of OS of HCC patients in the test datasets based on the signature; patients were divided into two risk group according to median risk score. (g) The receiver operating characteristic (ROC) curve for OS survival predictions for the signature in test set.

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