Prognostic Signature GXYLT2 Is Correlated with Immune Infiltration in Bladder Cancer

Table 1

Correlation analysis between GXYLT2 and relate genes and markers of immune cells in TIMER.

Description	Gene markers	None		Purity
		Cor		Cor
CD8+ T cell	CD8A	0.353		0.134
	CD8B	0.305		0.156
T cell (general)	CD3D	0.298		0.03	0.561
	CD3E	0.403		0.133
	CD2	0.389		0.126
B cell	CD19	0.381		0.185
	CD79A	0.405		0.187
Monocyte	CD86	0.575		0.386
	CD115 (CSF1R)	0.656		0.502
TAM	CCL2	0.574		0.411
	CD68	0.406		0.228
	IL10	0.619		0.488
M1 macrophage	INOS (NOS2)	0.174		0.131
	IRF5	-0.107		-0.105
	COX2 (PTGS2)	0.127		0.031	0.549
M2 macrophage	CD163	0.693		0.565
	VSIG4	0.679		0.537
	MS4A4A	0.668		0.531
Neutrophils	CD66b (CEACAM8)	0.02	0.683	0.047	0.372
	CD11b (ITGAM)	0.638		0.485
	CCR7	0.044	0.378	-0.06	0.254
Natural killer cell	KIR2DL1	0.221		0.081	0.122
	KIR2DL3	0.229		0.057	0.278
	KIR2DL4	0.21		0.026	0.619
	KIR3DL1	0.196		0.067	0.201
	KIR3DL2	0.18		0.031	0.558
	KIR3DL3	0.031	0.53	-0.014	0.794
	KIR2DS4	0.18		0.04	0.439
Dendritic cell	HLA-DPB1	0.513		0.309
	HLA-DQB1	0.431		0.225
	HLA-DRA	0.451		0.243
	HLA-DPA1	0.469		0.278
	BDCA-1 (CD1C)	0.266		0.082	0.117
	BDCA-4 (NRP1)	0.48		0.38
	CD11c (ITGAX)	0.641		0.479
Th1	T-bet (TBX21)	0.375		0.143
	STAT4	0.435		0.206
	STAT1	0.335		0.156
	IFN-γ (IFNG)	0.272		0.089	0.0891
	TNF-α (TNF)	0.282		0.16
Th2	GATA3	-0.387		-0.266
	STAT6	-0.179		-0.125
	STAT5A	0.28		0.122
	IL13	0.185		0.041	0.434
Tfh	BCL6	-0.109		-0.08	0.125
	IL21	0.172		0.092	0.0782
Th17	STAT3	0.393		0.273
	IL17A	-0.098		-0.157
Treg	FOXP3	0.446		0.277
	CCR8	0.45		0.297
	STAT5B	0.214		0.226
	TGFβ (TGFB1)	0.357		0.261
T cell exhaustion	PD-1 (PDCD1)	0.394		0.17
	CTLA4	0.391		0.168
	LAG3	0.394		0.186
	TIM-3 (HAVCR2)	0.602		0.42
	GZMB	0.369		0.118

was considered to be statistically significant (, , and ).