Low EBI3 Expression Promotes the Malignant Degree of Gastric Cancer
Table 1
Relationship between EBI3 expression and clinicopathological characteristics of GC patients.
Characteristic
()
EBI3-()
EBI3+()
value
Gender
0.228
0.633
Male
266
142 (53.4%)
124 (46.6%)
Female
87
49 (56.3%)
38 (43.7%)
Age
0.27
0.869
<60
128
70 (54.7%)
58 (45.3%)
≥60
225
121 (53.8%)
104 (46.2%)
Histological type
3.666
0.300
Tubular
8
3 (37.5%)
5 (62.5%)
Mixed and mucinous
94
45 (47.9%)
49 (54.1%)
Signed ring cell
185
103 (55.7%)
82 (44.3%)
Others
66
40 (60.6%)
26 (39.4%)
Differentiation
2.950
0.399
Well
10
3 (30.0%)
7 (70.0%)
Middle
141
74 (52.5%)
67 (47.5%)
Poor
182
103 (56.6%)
79 (43.4%)
Others
20
11 (55.0%)
9 (45.0%)
TNM stage
29.840
<0.001
0
7
0 (0.0%)
7 (100.0%)
54
19 (35.2%)
35 (64.8%)
127
63 (49.6%)
64 (50.4%)
134
84 (62.7%)
50 (47.3%)
31
25 (80.6%)
6 (19.4%)
T
19.951
0.001
Tis
7
0 (0.0%)
7 (100.0%)
T1
26
9 (34.6%)
17 (65.4%)
T2
72
32 (44.4%)
40 (55.6%)
T3
219
130 (59.4%)
89 (40.6%)
T4
29
20 (69.0%)
9 (31.0%)
N
19.039
<0.001
N0
120
49 (40.8%)
71 (59.2%)
N1
67
36 (53.7%)
31 (46.3%)
N2
76
42 (55.3%)
34 (44.7%)
N3
90
64 (71.1%)
26 (28.9%)
M
3.276
0.070
M0
331
175 (52.9%)
156 (47.1%)
M1
22
16 (72.7%)
6 (27.3%)
Preoperative CEA (ng/ml)
1.132
0.568
≤5
119
63 (52.9%)
56 (47.1%)
>5
42
20 (47.6%)
22 (52.4%)
Unknown
192
108 (56.3%)
84 (43.7%)
Preoperative CA199 (U/ml)
0.919
0.632
≤37
126
64 (50.8%)
62 (49.2%)
>37
26
14 (53.8%)
12 (46.4%)
Unknown
201
113 (56.2%)
88 (43.8%)
Statistical analyses were performed by the Pearson test. TNM stage: tumor node metastasis stage, CEA: carcinoembryonic antigen, CA199: carbohydrate antigen 19-9. is considered significant.
